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Wnt/β-catenin signaling pathway and its role in hepatocellular carcinoma

ZHANG Xufeng, YU Liang, LU Yi

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 216-228 doi: 10.1007/s11684-008-0042-x

Abstract: interacting components have been observed and their exact functions approached, thus ensuring the most complicatedunderstanding of this pathway in normal organism development and disorders.In hepatocellular carcinoma (HCC), with a deeply understanding of this pathway, more and more genes whichIn this review, we will focus on a mostly updated understanding of this pathway and its observed role

Keywords： interacting     complicated understanding     embryogenesis     activation     organism development    

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An analytical method for calculating torsional constants for arbitrary complicated thin-walled cross-sections

DU Baisong, GE Yaojun, ZHOU Zheng

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 3,   Pages 293-297 doi: 10.1007/s11709-007-0038-7

Abstract: In this paper, an analytical method is proposed for calculating torsional constants for complicated thin-walledFinally, a complicated thin-walled cross-section is given as a valid numerical example to verify the

Keywords： homogeneous     complicated thin-walled     numerical example     advantage     torsional function    

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Study of base friction simulation tests based on a complicated engineered bridge slope

Liu HE, Guang WU, Hua WANG

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 4,   Pages 393-397 doi: 10.1007/s11709-012-0174-6

Abstract: The model is based on similarity principles and the geological conditions of a complicated bridge slope

Keywords： base friction test     slope stability evaluation     bridge slope    

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The effect of orbital radiation therapy on thyroid-associated orbitopathy complicated with dysthyroid

Yang Wang, Huifang Zhou, Xianqun Fan

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 359-364 doi: 10.1007/s11684-017-0528-5

Abstract: The possible effects of radiotherapy on TAO, especially complicated with DON, are reviewed.

Keywords： thyroid-associated orbitopathy     dysthyroid optic neuropathy     orbital radiation therapy    

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From understanding to designing soundscapes

Jian KANG

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 4,   Pages 403-417 doi: 10.1007/s11709-010-0091-5

Abstract: Soundscape represents a step change in the field of environmental acoustics in that it combines physical, social, and psychological approaches. Although the term soundscape was introduced in the 1960s, significant attention to it has mainly been paid in the last decade or so in the community of environmental acoustics by researchers and recently by practitioners including policy makers. This paper explores the current situation and future challenges in soundscape. Starting with a framework on research and practical needs in soundscape and a brief introduction of some recent/current networks, activities, projects, and publications, this paper then presents a systematic review of recent progress in soundscape research and practice. A short review of the soundscape research in China is also given.

Keywords： soundscape     environment     sound     design     urban     landscape    

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Optimization transformation of complicated ventilation system in integration of mine

Zhang Futao

Strategic Study of CAE 2011, Volume 13, Issue 11,   Pages 68-71

Abstract:

As a resource integration mine, there were many problems in Tangshangou Mine such as complex ventilation system and much hidden danger. By determining the ventilation resistance and fan performance test and reasonable evaluation of mine ventilation system, the problems of original mine ventilation system were found out and analyzed, and an optimizing and transforming scheme for ventilation system was proposed. The results showed that the resistance of mine ventilation system was reduced and the stability and ability of fighting against natural calamities of mine ventilation network were improved.

Keywords： integration of mine     complicated ventilation system     optimization transformation    

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Air pollution complex: Understanding the sources, formation processes and health effects

Min Shao,Shuxiao Wang,Armistead G. Russell

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0883-5

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Fundamental frequency and testing mode of complicated elastic clamped-plate vibration

QI Hongyuan, GUAN Yiduo

Frontiers of Mechanical Engineering 2008, Volume 3, Issue 4,   Pages 360-364 doi: 10.1007/s11465-008-0084-4

Abstract: Aimed at the modal analysis of complicated elastic clamped-plates, a trigonometric interpolation methodof conformal mapping is applied to set up the mapping function between a complicated region and a unitdish region, and the fundamental frequency of the complicated vibrating region is analyzed with the

Keywords： multi-point excitation     rectangle-plate     single-point     processing technology     trigonometric interpolation    

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Atomistic understanding of interfacial processing mechanism of silicon in water environment: A ReaxFF

Frontiers of Mechanical Engineering 2021, Volume 16, Issue 3,   Pages 570-579 doi: 10.1007/s11465-021-0642-6

Abstract: However, the understanding regarding the micro dynamic process is still unclear due to the limitations

Keywords： silicon     ReaxFF     molecular dynamics     friction     damage    

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Culturomics and metagenomics: In understanding of environmental resistome

Monika Nowrotek, Łukasz Jałowiecki, Monika Harnisz, Grażyna Anna Płaza

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 3, doi: 10.1007/s11783-019-1121-8

Abstract:

State of the art of culturomics and metagenomics to study resistome was presented.

The combination of culturomics and metagenomics approaches was proposed.

The research directions of antibiotic resistance study has been suggested.

Keywords： Culturomics     Metagenomics     Antibiotic resistance     Resistome    

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Effect of styrene-butadiene-styrene copolymer on the aging resistance of asphalt: An atomistic understanding

Frontiers of Structural and Civil Engineering 2021, Volume 15, Issue 5,   Pages 1261-1276 doi: 10.1007/s11709-021-0761-5

Abstract: To reveal the potential influence of styrene-butadiene-styrene (SBS) polymer modification on the anti-aging performance of asphalt, and its mechanism, we explored the aging characteristics of base asphalt and SBS-modified asphalt by reaction force field (ReaxFF) and classical molecular dynamics simulations. The results illustrate that the SBS asphalt is more susceptible to oxidative aging than the base asphalt under oxygen-deficient conditions due to the presence of unsaturated C=C bonds in the SBS polymer. In the case of sufficient oxygen, the SBS polymer inhibits the oxidation of asphalt by restraining the diffusion of asphalt molecules. Compared with the base asphalt, the SBS asphalt exhibits a higher degree of oxidation at the early stage of pavement service and a lower degree of oxidation in the long run. In addition, SBS polymer degrades into small blocks during aging, thus counteracting the hardening of aged asphalt and partially restoring its low-temperature cracking resistance.

Keywords： SBS asphalt     oxidative aging     asphalt hardening     ReaxFF     molecular dynamics    

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Recent advances in understanding genetic variants associated with economically important traits in sheep

Song-Song XU, Meng-Hua LI

Frontiers of Agricultural Science and Engineering 2017, Volume 4, Issue 3,   Pages 279-288 doi: 10.15302/J-FASE-2017151

Abstract: Sheep are one of the most economically important domesticated animals for human society. However, genetic improvements for the key traits associated with meat, growth, milk, wool, reproduction, horns and tails progress slowly using conventional crossbreeding methods. With the development and utilization of high-throughput screening technologies over the last decade, a list of functional genes and genetic variants associated with these traits has been identified. This review covers recent genome-wide studies on sheep productive traits using high-throughput screening technologies, including those based on single-nucleotide polymorphisms and copy number variants at the whole-genome level (e.g., genome-wide association studies), transcriptome and DNA methylation sequences. Additionally, comprehensive information on functional genes and genetic variants associated with economically important traits in sheep is provided.

Keywords： sheep     high-throughput screening     productive traits     genome-wide studies    

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Improved film evaporator for mechanistic understanding of microwave-induced separation process

Xin Gao, Dandan Shu, Xingang Li, Hong Li

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 759-771 doi: 10.1007/s11705-019-1816-1

Abstract: In addition the depth understanding of the separation mechanisms is great importance for better utilizationEffects of operating parameters are also investigated to trigger further mechanism understanding on the

Keywords： process intensification     microwave     falling film evaporation     separation     azeotrope    

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Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 522-526 doi: 10.1007/s11684-016-0485-4

Abstract:

Ulcerative colitis (UC) is a chronic inflammatory bowel disease with continuous or recurrent symptoms. A 42-year-old male patient with intermittent diarrhea accompanied by bloody mucopurulent stools was admitted to our hospital. The diagnosis of UC was confirmed by a combination of laboratory examination, colonoscopy, and histological assay. The patient developed herpes zoster in the hospital, which challenged traditional treatments. Therefore, we performed an autologous bone marrow cells to modulate the immune system with his permission. Autologous bone marrow mononuclear cells were collected and injected locally into the bowel mucosa, and subsequently injected systemically through a peripheral vein. After the patient underwent auto bone marrow mononuclear cells transplantations twice, the patient’s symptoms were alleviated. Furthermore, he recovered from hematochezia, and his hypersensitive C reactive protein decreased. Colonoscopy results showed reduced lesions and decreased areas with bleeding and edema in the sigmoid colon and rectum. No recurrence occurred in the subsequent two years, but long-time monitoring is still necessary for the prophylaxis of colorectal cancer.

Keywords： autograft     bone marrow stem cells     ulcerative colitis     cell therapy    

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Current understanding and applications of the cold sintering process

Tong Yu, Jiang Cheng, Lu Li, Benshuang Sun, Xujin Bao, Hongtao Zhang

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 654-664 doi: 10.1007/s11705-019-1832-1

Abstract: In traditional ceramic processing techniques, high sintering temperature is necessary to achieve fully dense microstructures. But it can cause various problems including warpage, overfiring, element evaporation, and polymorphic transformation. To overcome these drawbacks, a novel processing technique called “cold sintering process (CSP)” has been explored by Randall et al. CSP enables densification of ceramics at ultra-low temperature (≤300°C) with the assistance of transient aqueous solution and applied pressure. In CSP, the processing conditions including aqueous solution, pressure, temperature, and sintering duration play critical roles in the densification and properties of ceramics, which will be reviewed. The review will also include the applications of CSP in solid-state rechargeable batteries. Finally, the perspectives about CSP is proposed.

Keywords： cold sintering process     processing variables     solid-state rechargeable batteries    

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Title Author Date Type Operation

Wnt/β-catenin signaling pathway and its role in hepatocellular carcinoma

ZHANG Xufeng, YU Liang, LU Yi

Journal Article

An analytical method for calculating torsional constants for arbitrary complicated thin-walled cross-sections

DU Baisong, GE Yaojun, ZHOU Zheng

Journal Article

Study of base friction simulation tests based on a complicated engineered bridge slope

Liu HE, Guang WU, Hua WANG

Journal Article

The effect of orbital radiation therapy on thyroid-associated orbitopathy complicated with dysthyroid

Yang Wang, Huifang Zhou, Xianqun Fan

Journal Article

From understanding to designing soundscapes

Jian KANG

Journal Article

Optimization transformation of complicated ventilation system in integration of mine

Zhang Futao

Journal Article

Air pollution complex: Understanding the sources, formation processes and health effects

Min Shao,Shuxiao Wang,Armistead G. Russell

Journal Article

Fundamental frequency and testing mode of complicated elastic clamped-plate vibration

QI Hongyuan, GUAN Yiduo

Journal Article

Atomistic understanding of interfacial processing mechanism of silicon in water environment: A ReaxFF

Journal Article

Culturomics and metagenomics: In understanding of environmental resistome

Monika Nowrotek, Łukasz Jałowiecki, Monika Harnisz, Grażyna Anna Płaza

Journal Article

Effect of styrene-butadiene-styrene copolymer on the aging resistance of asphalt: An atomistic understanding

Journal Article

Recent advances in understanding genetic variants associated with economically important traits in sheep

Song-Song XU, Meng-Hua LI

Journal Article

Improved film evaporator for mechanistic understanding of microwave-induced separation process

Xin Gao, Dandan Shu, Xingang Li, Hong Li

Journal Article

Autologous bone marrow stem cell transplantation for the treatment of ulcerative colitis complicated

Hang Xiang,Xiaomei Zhang,Chao Yang,Wenhuan Xu,Xin Ge,Rong Zhang,Ya Qiu,Wanjun Sun,Fan Li,Tianyuan Xiang,Haixu Chen,Zheng Wang,Qiang Zeng

Journal Article

Current understanding and applications of the cold sintering process

Tong Yu, Jiang Cheng, Lu Li, Benshuang Sun, Xujin Bao, Hongtao Zhang

Journal Article